Antifungal Drugs

Antifungal drugs.

Working in the medium of batik, Paul Nzalamba creates images that are drawn from his native country, Uganda, and that reflect the strength, struggle, and beauty of all people, especially children and adolescents. We chose to use his “At Play” (1988) to show a modern, indigenous artist’s work that illustrates the color and joy of such artists. Mr. Nzalamba’s works are on display at his studio in...

Antifungal Drugs

GENERIC NAME PAGE Amphotericin B 596 Butoconazole 601 Capsofungin 601 Ciclopirox 602 Clotrimazole 600 Econazole 601 Fluconazole 598 Flucytosine 601 Griseofulvin 602 Itraconazole 599 Ketoconazole 599 GENERIC NAME PAGE Miconazole 600 Naftifine hydrochloride 602 Nystatin 598 Oxiconazole nitrate 601 Sulconazole nitrate 601 Terbinifine hydrochloride 602 Terconazole 601 Tioconazole 601 Tolnaftate 602...

Antifungal application of non - antifungal drugs 1

Echinocandin antifungal drugs.

The echinocandins are large lipopeptide molecules that are inhibitors of beta-(1,3)-glucan synthesis, an action that damages fungal cell walls. In vitro and in vivo, the echinocandins are rapidly fungicidal against most Candida spp and fungistatic against Aspergillus spp. They are not active at clinically relevant concentrations against Zygomycetes, Cryptococcus neoformans, or Fusarium spp. No ...

Introduction to antifungal drugs.

In the United States, only 10 antifungal drugs are currently approved by the Food and Drug Administration (FDA) for the therapy of systemic fungal infections. As shown in table 1, these drugs belong to 3 principal classes: polyenes, pyrimidines, and azoles. Drugs that belong to other classes are also approved as topical antifungal drugs, but will not be considered further here. Although convent...